Intensive cellular training with IHHT(Interval Hypoxia Hyperoxia Therapy)

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Natural and innovative method for more energy!

Increases performance and vitality
Slows down the aging process
Increases well-being
Supports weight loss by stimulating fat metabolism

How does IHHT work?

You lie completely relaxed on your bed and alternately breathe hypoxic (low oxygen content) and hyperoxic (enriched oxygen) air through a breathing mask.
The oxygen concentration in the body is constantly measured and monitored using a finger clip
(pulse oximetry).

The oxygen content can be reduced to 9%, which corresponds to an altitude of around 6,700 meters. While the air we breathe contains around 21% oxygen, in the hyperoxic phase the oxygen content can increase to as much as 32%.


Healthy mitochondria protect themselves from the increased oxygen concentration with antioxidants. However, damaged mitochondria cannot withstand this stress and die. This deliberately destroys the damaged mitochondria, which in turn results in a lack of energy in the cells for several days. It is this lack of energy that provides an important impulse for the accelerated proliferation of new, healthy mitochondria.

With regular treatments you can:

  • Increase your efficiency and vitality
  • Slow down the aging process
  • Increase your well-being

Nobel Prize for Hypoxia Research

IHHT is not an entirely new method of therapy. It really became famous during the 1968 Summer Olympics in Mexico. At that time, many athletes moved their training to the mountains to prepare for competitions at an altitude of 2,300 meters. People knew about the beneficial effect of mountain air on improving physical performance, but they could not explain how it happened. It was the discovery of the hypoxia factor HIF-1-alpha that provided an explanation for the overall effect. The hypoxia factor HIF-1-alpha leads to the activation of genes that compensate for the lack of oxygen in the tissue and ensures energy production in the cells.


Professor Gregg L. Semenza, the discoverer of HIF-1-alpha and winner of the Nobel Prize in Medicine in 2019, and two colleagues talk about more than 300 genes that are directly or indirectly affected by the hypoxia factor.

The hypoxia factor works to improve oxygen supply and utilization, i.e. energy delivery, throughout the body. Healthy mitochondria can replicate under the influence of hypoxia and immediately become fully functional. At the same time, the breakdown (autophagy) of old and damaged mitochondria is accelerated. This effect on the entire cellular metabolism is one of the reasons for the success of IHHT.

Who is this treatment for?

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Controlled hypoxia – the key to cell activation

Hypoxia means a reduced supply of oxygen to the cells of the body. In the mountains, a lower oxygen content in the air we breathe occurs naturally due to the reduced air pressure and lower density of the air in the atmosphere. If the air pressure in the lowlands remains unchanged, a reduction in the supply of oxygen to the arterial blood will only be possible if the ratio of nitrogen to oxygen in the air we breathe changes. Modern hypoxia devices use this procedure.

IHHT is a technical term for simulated altitude training with a hypoxic device. The patient inhales a respiratory air mixture with reduced oxygen content for several minutes using a breathing mask. During this time, the oxygen content in the blood (SpO2) decreases very slowly to a specific range. This controlled hypoxia is different from uncontrolled hypoxia, such as occurs in obstructive sleep apnea.

During IHHT, various physical adaptation processes are initiated that do not cause any damage and lead to an overall increase in performance.

What positive effects can be expected?

MITOCHONDRIA

Why are healthy mitochondria so important?

Oxidative damage to mitochondrial DNA (mtDNA), leading to so-called mitochondrial dysfunction, is one of the main factors of human aging and the development of chronic diseases [1]. This is counteracted by continuous mitochondrial renewal. In this way, IHT counteracts oxidative stress, increases the efficiency of oxidative metabolism, slows down the aging process and prevents/delays the development of age-related diseases [2].


[1] Picard, M.; Turnbull, D.M. Linking the Metabolic State and Mitochondrial DNA in Chronic Disease, Health, and Aging. Diabetes 2013, 62, 672–678, doi:10.2337/db12-1203.

[2] Marshall, R.P.; Droste, J.-N.; Giessing, J.; Kreider, R.B. Role of Creatine Supplementation in Conditions Involving Mitochondrial Dysfunction: A Narrative Review. Nutrients 2022, 14, 529. 

The human body consists of about 80 trillion cells. Mitochondria are the energy centers of our body. They are found in every cell and they are the ones that supply the body with the energy necessary for life and the functioning of every organ. For example, a nerve cell has about 10,000 mitochondria, and an egg cell has up to 100,000 mitochondria. Mitochondria in the heart muscle make up about 36% of its total mass. They also perform a number of other important functions, such as detoxifying our body.

Your mitochondria are real power plants, because based on their mass, they produce between 10,000 and 50,000 times more energy than the sun. For us humans, this means that our mitochondria produce about the same amount of ATP as our body weight every day. Unlike other organelles, mitochondria have their own DNA (mtDNA). Although it is much shorter than the DNA in the cell nucleus, it occurs in several copies. Thanks to their own genome, mitochondria can reproduce independently of the cell. As the power plants of our cells, mitochondria are primarily responsible for providing us with energy. If many of them become damaged, energy production in our cells becomes increasingly inefficient. Over the years, the lack of energy becomes increasingly noticeable: for example, in the form of increased fatigue and exhaustion. During cellular respiration, free radicals are formed, which in physiological quantities are important for various processes in our body. However, in excess, they lead to oxidative stress, which damages the cell and its organelles.

To prevent this, mitochondria are equipped with a good protective system (including antioxidants), the activity of which is regulated by the production of free radicals.

The goal of IHHT is to increase the
number of healthy mitochondria
and suppress weak ones.

Irreversible: mitochondrial damage

The body’s ability to produce energy efficiently is severely limited on the one hand by the aging process and on the other by the lifestyle of the 21st century (oxidative stress due to deadlines, shortened sleep, sensory overload, poor diet, etc.). The result is mitochondrial damage, which can now be detected in one in three people aged 20 and over. Damaged mitochondria not only produce less energy, but also release more free radicals.

The diverse tasks of mitochondria

Until now, mitochondria have been known mainly as the cellular powerhouse, generating energy from fats and glucose using oxygen. However, recent studies show that mitochondria have a number of other functions. They coordinate over 500 different chemical reactions in our body, monitoring and regulating the environment in the cell. Among other things, mitochondria play a protective role in the cell, are important for signaling in the innate immune system to recognize pathogens and trigger inflammation, and are involved in various processes in the central
nervous system.

IHHT is a specific aerobic training that increases the number of intact mitochondria

IHHT Cellular Training
Repairs Cells

Interval hypoxia-hyperoxia therapy destroys – deliberately and consciously – damaged, old mitochondria, while promoting the proliferation of new, healthy mitochondria in cells. Cell protection is also increased by increasing the share of the antioxidant Q10 by up to 40%.

IHHT causes better oxygenation of the body and maximizes energy production at the cellular level.

A better energy supply leads to greater fat burning and helps people lose weight.

Organs are better supplied with blood, and the autonomic nervous system is balanced.

IHHT also has a positive effect on the brain, increasing concentration and efficiency.

More mitochondria and a better supply of organs with oxygen and nutrients increase the efficiency of the cardiovascular system (strengthening the heart, creating new blood vessels).

IHHT promotes regeneration, activates the parasympathetic nervous system, and thus helps improve sleep.

Regular cell training is important!

Rejuvenation and vitality
starts in the cells!

Only regular cell training also means lasting regeneration of cell metabolism. 10 IHHT applications, each lasting 45 minutes, are comparable to the physiological effects of a four-week stay in the Alps and lead to an improvement in the body for up to three months.

Combine IHHT for optimal results

To ensure your body gets the best benefits from IHHT altitude training, combine it with molecular hydrogen inhalation or cryostimulation for additional performance-enhancing effects, optimized blood circulation and faster recovery.

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